BIO 004 · Human Anatomy

The Nerve Plexuses

Block 5 · Module 5: The Peripheral Nervous System, the Nerve Plexuses

A brief reference for the nerve plexuses. A plexus is a network where the anterior rami of spinal nerves regroup before traveling to the body. This page covers the principal plexuses at a general level: where each one forms and what region it serves, so you can predict the area of the body affected if a plexus is damaged.

How to use this sheet Toggle the toolbar above. Notes prints the full reference for review. Study prints as a fill-in-the-blank worksheet. Print it, then write each definition while you watch the video or read your book. Quiz me is on-screen typing practice: type the term, click Reveal to check yourself. The comparison grids respond to Study and Quiz too, with a Reveal button on each row.

Practice Spaced Recall

The Foundations video gives you a complete foundational understanding of this topic, enough on its own for a foundational course. Learn it first, then move on to the Deep dive, which adds the majors-level depth for this course.


By the end
  1. Define a nerve plexus and explain why the anterior rami regroup.
  2. Name the principal nerve plexuses and the spinal nerves that form each.
  3. Predict the region of the body affected if a given plexus is damaged.

Your pre-work

Work through these the evening before class. None of it is turned in. It is how you learn the material and build your spaced recall.

This is more than a checklist. Ticking these boxes is the start, not the finish. Committing this material to memory and being able to apply it takes considerable time and repeated effort. You are not done when the boxes are checked. Put in the real hours, and keep coming back for frequent recall and review until the material is genuinely yours.

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The four plexuses in place

Add a posterior view showing where the cervical, brachial, lumbar, and sacral plexuses sit along the spine.

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Anterior rami forming a plexus

Add a diagram showing the anterior rami of several spinal nerves weaving into a plexus.

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Regions served

Add a body map shading the region each principal plexus supplies.


What a Nerve Plexus Is

Most spinal nerves do not run straight to their targets. The anterior rami of neighboring spinal nerves first weave together into a network called a plexus, then sort their axons into the nerves that leave it. The thoracic region is the exception.


The Principal Nerve Plexuses

Each plexus is formed by a known set of spinal nerves and serves a known region of the body. Compare them.

The principal nerve plexuses compared
PlexusFormed byRegion served
Cervical plexusthe anterior rami of C1 to C4, with a contribution from C5the skin and muscles of the neck and the upper shoulders; it also gives rise to the phrenic nerve, the motor supply to the diaphragm
Brachial plexusthe anterior rami of C5 to C8 and T1the shoulder and the entire upper limb
Lumbar plexusthe anterior rami of L1 to L4the anterolateral abdominal wall, the external genitals, and part of the lower limb
Sacral plexusthe anterior rami of L4 to L5 and S1 to S4the buttocks, the perineum, and most of the lower limb
Coccygeal plexusthe anterior rami of S4 to S5 and the coccygeal nervesa small area of skin over the coccyx

Predicting the Effect of Plexus Damage

Because each plexus serves one region, the location of a plexus injury predicts the region of the body that loses movement and sensation. This is the level of detail to know for this course.

The region affected by damage to each plexus
Plexus damagedRegion affected
Cervical plexusweakness or numbness of the neck and shoulder; if the phrenic nerve is involved, the diaphragm on that side is weakened and breathing is affected
Brachial plexusweakness and sensory loss across the shoulder and the whole upper limb on that side
Lumbar plexusweakness and sensory loss of the lower abdominal wall and the front and inner surfaces of the thigh
Sacral plexusweakness and sensory loss of the buttock, the back of the thigh, and the leg and foot
Coccygeal plexusnumbness of the small patch of skin over the coccyx

See also: The Peripheral Nervous System for nerve structure and the spinal nerves, and The Spinal Cord for the roots these rami arise from.

Study questions

Work on answering these in writing, in your own words. They are the questions to bring to class, and good practice for the reasoning the exams ask for.

  1. Name the four major nerve plexuses and the region of the body each one supplies.
  2. Explain what a plexus is, and why nerves regroup into one rather than running straight from the cord.
  3. Predict which region would be affected if the brachial plexus were injured, and which if the lumbar plexus were.
  4. Compare the cervical and sacral plexuses by the body region each one serves.
Dr. Sharilyn Rennie BIO 004 · Block 5 · Module 5