BIO 304 . WEEK 4 OF 8 . DISCUSSION

When the message fails

Pick a disease or toxin that disrupts muscle contraction or nervous conduction, locate where in the cycle it strikes, then predict the symptoms from first principles.

Initial post due Friday. Replies due Sunday. Substantive replies build on or respectfully challenge a classmate's thinking.

Deadlines and expectations

Three dates to put on your calendar.

Prompt opens

Wed, Jul 1

Wednesday, 12:00 AM

Initial post due

Fri, Jul 3

Friday, 11:59 PM

Replies due

Sun, Jul 5

Sunday, 11:59 PM

Your prompt

What to write about.

This week we built the sliding filament theory of muscle contraction and the action potential. Both depend on a precise chemical signal arriving at the right place at the right time.

Pick one disease or toxin that disrupts either muscle contraction or nervous conduction. Examples: myasthenia gravis, organophosphate poisoning, multiple sclerosis, botulinum toxin, malignant hyperthermia, tetanus, Lambert-Eaton syndrome.

In your initial post (200-300 words):

  1. Name the condition and a one-sentence summary.
  2. Identify the exact step in the cycle where it disrupts function. Be precise (e.g., "blocks nicotinic ACh receptors at the neuromuscular junction"; "prevents synaptic vesicle release").
  3. Predict the patient's symptoms from first principles, not from a list you found online.
  4. Note one treatment and why it targets that step.
Replies

What makes a reply substantive.

  • Substantive: at least 75 words. Goes beyond "I agree" or "nice post."
  • Builds or challenges: extend a classmate's idea with new information, OR respectfully push back with reasoning.
  • Cite or apply: reference the OpenStax section, your textbook reading, or a topic from this week's pre-work.
  • At least two replies to different classmates by Sunday.
Ready to post

Open the Canvas thread for Week 4.

Initial post due Friday by 11:59 PM. Two replies due Sunday by 11:59 PM.

Open the Canvas discussion →