BIO 304 · Week 2 · Interactive Workbook

Muscle & Nervous Tissue Overview

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Part 1 of 4 · Recall

Fill in the blanks

Type the term that completes each statement, using the word bank. Pull it from memory first.

Word bank

StriatedMultinucleateWhereOne central nucleusInvoluntaryWhereOne central nucleusWhereSoma (cell body)Axon terminalMyelin sheathAstrocyteMicrogliaSchwann cell

  1. visible bands from organized sarcomeres
  2. long fibers fused from many myoblasts
  3. attaches to bone; moves the skeleton
  4. short branching cells
  5. autorhythmic; ANS modulates rate
  6. heart wall only
  7. small cells, single nucleus
  8. walls of hollow organs and vessels
  9. nucleus + most organelles; integration point
  10. releases neurotransmitter at the synapse
  11. fatty insulation on axon; speeds conduction
  12. most numerous; blood-brain barrier, K+ buffering
  13. CNS macrophages; immune surveillance
  14. myelinates PNS axons (one cell wraps one segment of one axon)

Define it: high-yield vocabulary

Write a clear definition in your own words for each term.

  1. Skeletal muscle
  2. Cardiac muscle
  3. Smooth muscle
  4. Striations
  5. Voluntary control
  6. Involuntary control
  7. Neuron
  8. Dendrite
  9. Axon
  10. Neuroglia

Part 2 of 4 · Anatomy lab

Draw and label

Box A. Three muscle types side by side

Directions

  1. Left: Skeletal muscle. Draw long parallel cylindrical fibers with visible cross-striations. Place several nuclei at the edge of each fiber (multinucleate). Label striated, multinucleate, voluntary.
  2. Center: Cardiac muscle. Draw shorter branched cells with cross-striations. Show one or two central nuclei per cell. Show intercalated discs (thick lines at cell junctions). Label striated, branched, intercalated discs, involuntary.
  3. Right: Smooth muscle. Draw spindle-shaped cells with a single central nucleus. No striations. Label non-striated, single nucleus, involuntary.
  4. Under each, list one typical location: skeletal = limb muscles; cardiac = heart only; smooth = walls of hollow organs, blood vessels.
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Box B. Basic neuron

Directions

  1. Draw a neuron. Cell body (soma) with nucleus. Several short branched dendrites. One long axon. Axon terminals at the end.
  2. Add a myelin sheath wrapping segments of the axon with gaps (nodes of Ranvier) between segments.
  3. Label cell body, dendrite, axon, myelin sheath, node of Ranvier, axon terminal.
  4. Note next to the neuron: nervous tissue function = generate and conduct electrical signals; muscle tissue function = contract in response to signals.
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Structures to label

Label each on your drawing.

  1. Skeletal muscle fiber
  2. Cardiac muscle cell
  3. Smooth muscle cell
  4. Cross-striations
  5. Intercalated disc
  6. Multinucleate
  7. Single central nucleus
  8. Cell body (soma)
  9. Dendrite
  10. Axon
  11. Myelin sheath
  12. Node of Ranvier
  13. Axon terminal

Part 3 of 4 · Physiology lab

Reason it through

A. Muscle comparison table

Intercalated discs contain gap junctions that allow ions to flow between cardiac cells. Explain why this is functionally critical for the heart.
Both skeletal and cardiac muscle are striated. What does that visible pattern tell us about how they generate force? Why does smooth muscle look different even though it also uses actin and myosin?

B. Synthesis

1. Damaged skeletal muscle can be partly replaced by satellite cell activation; damaged cardiac muscle is replaced by scar (non-contractile) tissue. Predict the long-term consequences of a heart attack on cardiac function, and contrast with recovery from a torn skeletal muscle.
2. Smooth muscle is found in the wall of the gut and contracts in slow waves (peristalsis). Predict what happens to digestion in a region of gut where the smooth muscle is damaged.
3. Action potentials in neurons travel at speeds up to 100 meters per second in myelinated axons. Predict what happens to signal speed when myelin is damaged (e.g., multiple sclerosis) and what symptoms might result.

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