right atrium near SVC; intrinsic rate 60-100; primary pacemaker
interatrial septum; intrinsic rate 40-60; delays signal ~0.1s
down either side of septum
allows atrial systole to finish before ventricular contraction begins
membrane drifts upward toward threshold
K+ channels open
fast Na+ channels open; rapid depolarization
Ca²⁺ influx balances K+ efflux; sustained depolarization — this is unique to cardiac muscle
resting potential restored; ready to fire again
each beat is followed by relaxation and refilling
ventricular repolarization
normally < 0.12 s; widened in bundle branch block
norepinephrine on beta-1 receptors → speeds SA, increases contractility
parasympathetic dominates; intrinsic SA rate without ANS is ~100/min
some atrial beats not conducted
Define it: high-yield vocabulary
Write a clear definition in your own words for each term.
SA node
AV node
Bundle of His
Purkinje fibers
Autorhythmicity
Pacemaker potential
P wave
QRS complex
T wave
Cardiac refractory period
AV block
Part 2 of 4 · Anatomy lab
Draw and label
Box A. Conduction pathway
Directions
Draw a heart silhouette with all four chambers.
At the top of the right atrium, draw a small oval: the SA node (sinoatrial node). Label. Note: the natural pacemaker, fires at 60 to 100 bpm.
Show the signal spreading across both atria (small arrows), causing them to contract.
At the junction of atria and ventricles (in the interatrial septum, near the tricuspid valve), draw the AV node (atrioventricular node). Label. Note: delays the signal by about 0.1 second to let atria empty.
From the AV node, draw the bundle of His (AV bundle) descending through the interventricular septum. Label.
Split into right and left bundle branches.
End in the Purkinje fibers spreading throughout the ventricular walls. Label.
Add arrows showing the direction of signal flow: SA node, atria, AV node, bundle of His, bundle branches, Purkinje fibers, ventricles contract.
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Box B. Normal ECG
Directions
Draw a single normal ECG cycle (one heartbeat). x-axis is time, y-axis is voltage.
Start with a flat baseline. Draw a small upward bump: the P wave. Label.
After P, a brief flat segment (PR segment), then a tall sharp downward-upward-downward complex: the QRS complex. Label Q, R, S.
After QRS, another flat segment (ST segment), then a smaller rounded upward bump: the T wave. Label.
Annotate what each wave represents: P = atrial depolarization (atria contract); QRS = ventricular depolarization (ventricles contract); T = ventricular repolarization (ventricles relax).
Note: atrial repolarization is hidden inside the QRS complex.
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Box C. The cardiac cycle (one beat)
Directions
Draw two heart silhouettes side by side, both showing all four chambers.
Left silhouette: DIASTOLE (ventricles relaxed). Show atria contracting and pushing blood into ventricles. Tricuspid and mitral valves OPEN. Pulmonary and aortic valves CLOSED.
Right silhouette: SYSTOLE (ventricles contracted). Show ventricles squeezing blood out to lungs and body. Tricuspid and mitral valves CLOSED. Pulmonary and aortic valves OPEN.
Below the silhouettes, draw a pressure-time graph. Show LV pressure rising sharply during systole, falling during diastole. Show aortic pressure following LV during systole, holding higher during diastole (because of valve closure).
Label end-diastolic volume (EDV, max ventricle volume), end-systolic volume (ESV, min volume after contraction), and stroke volume (SV = EDV minus ESV).
Note: the heart sounds 'lub-dub' correspond to valve closure: lub = AV valves close at start of systole; dub = semilunar valves close at start of diastole.
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Structures to label
Label each on your drawing.
SA (sinoatrial) node
AV (atrioventricular) node
Bundle of His
Right bundle branch
Left bundle branch
Purkinje fibers
P wave
QRS complex
T wave
PR interval
ST segment
Atrial depolarization
Ventricular depolarization
Ventricular repolarization
Systole
Diastole
End-diastolic volume (EDV)
End-systolic volume (ESV)
Stroke volume
Part 3 of 4 · Physiology lab
Reason it through
A. Match ECG component to electrical event
1. The P wave.
2. The PR interval.
3. The QRS complex.
4. The ST segment.
5. The T wave.
6. A flat line between heartbeats (the baseline).
B. Synthesis
1. A patient is in third-degree (complete) heart block: the atria fire normally, but the signal does not pass through the AV node to the ventricles. The ventricles develop their own slower rhythm. Predict the ECG pattern (relationship between P waves and QRS complexes), and predict the heart rate and the patient's symptoms.
2. Atrial fibrillation: the atria depolarize chaotically at 400+ times per minute. The AV node filters most of these signals. Predict (a) what happens to the P wave on the ECG, (b) the regularity of QRS complexes, and (c) why patients are at high risk for stroke.
3. Ventricular fibrillation: ventricles depolarize chaotically. Unlike atrial fibrillation, this is a cardiac emergency. Explain mechanistically why V-fib is immediately life-threatening but A-fib is not, and why a defibrillator works to reset the heart.
Submit
Save as PDF, then upload to Canvas.
The exported PDF stamps your name and paste-attempt count. Drawn-here or hand-drawn diagrams only; typed or AI-generated diagrams are not accepted.